PADI3 Gene

Meaning

The PADI3 gene holds a quiet significance in the grand design of our hair, particularly for those with textured patterns. It directs the making of an enzyme, Peptidyl Arginine Deiminase Type III, which gently adjusts certain proteins like trichohyalin and filaggrin within the hair shaft. These adjustments are fundamental to the hair’s inherent structure and its characteristic curl, strength, and overall feel. For Black and mixed-race hair, understanding this gene offers a grounding perspective on why our strands behave as they do, moving beyond surface-level observations to appreciate the genetic blueprint. This foundational knowledge helps in systematizing hair care; knowing the intrinsic properties influenced by PADI3 allows for a more attuned approach to routines, ensuring products and methods truly align with the hair’s natural inclinations. Practically, recognizing the PADI3 gene’s subtle influence can refine daily practices, guiding choices that respect the hair’s unique formation, supporting a more informed and gentle relationship with one’s heritage-rich coils and curls. It helps us see that consistent, tailored care is a gentle conversation with our hair’s very make-up.